Um...sure!? Perl's motto is TMTOWTDI, and believe me, there are many ways to do anything you want to, but some are a little more streamlined that others.
Please remember that when posting a question (which in this forum typically involves code), be sure to post what you have written so far and tried, so that those trying to help you have something to go on. If you don't, then we can only assume you haven't tried anything yet and you may not get too many replies as this isn't a code writing service.
That said, there are modules to assist you in not only downloading the HTML data, but also with the parsing of the HTML to break it out into its tree so you can grab what you need. Once you have the data you need, then you can use another module (DBI) to plug it into your database.
Regards,
Jeff