As far as I know, Lotus Notes is a desktop application, but sugarcrm is a web application.
Are you trying to have your web application access data from a desktop application? While this MAY be possible, it's not really a good idea. Browsers are built to protect local data from being accessed by websites, and you won't bypass those security measures in a hurry.
I would seriously consider building a desktop application instead.
Not that that is going to be exactly easy. It will require an in-depth knowledge of both systems.
Or you could always try to find existing software to do this for you.
A
Google search usually doesn't fail.
(See the first link)