All the information you need on controls that use JavaScript for client side validation and any other .NET controls can be found in the
MSDN Library. This resource should get you pointed in the right direction....there are multiple articles on controls like the
RequiredFieldValidator which will do client side validation for you. Be sure to look into how you can group controls into one validation group so that you don't have too many validation controls doing the same thing. I recommend bookmarking the MSDN Library and using it as your primary resource when developing in .NET.
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Before you post your question.
-Frinny