System.IO.__Error.WinIOError in XmlSerializer constructor

[mzl]

On one of the machine, when bring up the application, the execption thrown
with the following message:
Could not find a part of the path
"C:\DOCUME~1\mosesjr\LOCALS~1\Temp\1i-ak8ur.0.cs"

and the call stack shows it's from the XmlSerializer ctor:
Source=mscorlib
StackTrace= at System.IO.__Error.WinIOError(Int32 errorCode, String str)
at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess
access, FileShare share, Int32 bufferSize, Boolean useAsync, String msgPath,
Boolean bFromProxy)
at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess
access, FileShare share)
at
System.CodeDom.Compiler.CodeCompiler.FromSourceBat ch(CompilerParameters
options, String[] sources)
at System.CodeDom.Compiler.CodeCompiler.FromSource(Co mpilerParameters
options, String source)
at
System.CodeDom.Compiler.CodeCompiler.System.CodeDo m.Compiler.ICodeCompiler.CompileAssemblyFromSource (CompilerParameters options, String source)
at System.Xml.Serialization.Compiler.Compile()
at System.Xml.Serialization.TempAssembly..ctor(XmlMap ping[] xmlMappings)
at System.Xml.Serialization.XmlSerializer..ctor(Type type, String
defaultNamespace)
at System.Xml.Serialization.XmlSerializer..ctor(Type type)

Any idea what's the cause for this to happen? Anti-virus, etc.? Please help.

Thank you in advanced